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ii) Primary culture of satellite cells with 5 ng/ml HGF, which received only the LASSS pre-treatment (at 1:8000, without peroxynitrite treatment), exhibited a cell-proliferation activity (evaluated by mRNA expression levels of MyoD and its counter-regulatory factor myogenin at 48-h and 72-h time-points) comparable to that of the positive control culture treated with 5 ng/ml control HGF without LASSS (just with the solvent

Other proposed mechanisms include direct interaction with cell surface integrins (particularly alpha-2-beta-1), effects on iron metabolism through copper-iron regulatory interactions, and epigenetic modifications

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Most cells, in contrast to epithelial cells, do not have a direct transport capacity for intact GSH